Abstract: OBJECTIVE To explore the effects of the quality control of the intravenous drugs for control of centralized dispensing-related infection in pharmacy intravenous admixture services (PIV AS), so as to provide the basis for prevention and control of the hospital infection. METHODS A total of 300 cases treated with the intravenous drug of PIV AS from Mar. to Dec. 2013, and 300 cases treated with the intravenous drug of PIV AS after the quality control from Mar. to Dec. 2014 were selected. The hospital infection of the patients before and after the quality control were observed, and the statistical results of hygiene rates of related items in PIV AS, air quality, hand hygiene of the staff and infection rate after using intravenous drug from PIV AS within the two years were compared. RESULTS The hygiene rates of five kinds of related items in 2014 were significantly better than those in 2013 (P<0.05). The qualified rate of air quality in PIV AS and hand hygiene rate of the staff in 2014 were significantly higher than those in 2013 (P<0.05). The error rate of intravenous medication in the PIV AS significantly reduced after the quality control management by the year 2014 (P<0.05). The hospital infection of 300 patients in general surgery treated with the intravenous drug of PIV AS after hospitalization in 2014 was significantly lower than that in 2013 (P＜0.05). CONCLUSION Quality control is very critical for hospital infection control, and it can optimize the system management of PIV AS, reduce the waste of drugs, and reduce the occurrence of hospital infections.