Abstract: OBJECTIVE To study the changes of serum and urine inflammatory indicators of urinary tract infected patients with hypertensive cerebral hemorrhage, in order to provide evidence for improvement of the cure rate. METHODS A total of 42 cases of hypertensive cerebral hemorrhage with urinary tract infections in hospital from Dec. 2014 to Dec. 2015 were selected as test group, and 42 cases of hospitalized hypertensive cerebral hemorrhage patients without infection at the same period were selected as control group. The serum and urine inflammatory indicators of the two groups of patients were measured at different time points before and after treatment, and the changes of serum and urine inflammatory related indicators of urinary tract infected patients with hypertensive cerebral hemorrhage. The data were analyzed by SPSS 18.0. RESULTS The PCT and CRP levels of test group were significantly higher than those of control group (P<0.05). The IL-6, IL-2 and TNF-α levels of the two group before treatment were significantly higher than those of control group (P<0.05). The IL-6, IL-2 and TNF-α levels of test group had no significant difference compared with those of control group. CONCLUSION The serum and urine inflammatory indicators of urinary tract infected patients with hypertensive cerebral hemorrhage have great changes, and effective measures should be taken for treatment based on test results.