幽门螺杆菌感染与胃癌发生发展相关性研究

Correlation between Helicobacter pylori infection and occurrence and development of gastric cancer

  • 摘要: 目的 对胃肠恶性肿瘤进行手术的老年患者进行跟踪研究,分析老年患者在手术恢复阶段发生肺部感染的原因及治疗方法,以降低肺部感染率。方法 调查2013年1-12月入院治疗的胃肠恶性肿瘤老年患者75例,对手术过程及术后恢复进行跟踪,分析发生感染的原因和危险因素,制定预防措施。结果 75例胃肠恶性肿瘤老年患者中发生肺部感染16例,感染率21.3%;肺部感染患者中男女比例约为2∶1,男性10例、女性6例;由于肺部感染导致患者死亡10例,病死率13.3%;卧床时间、留置置管时间、气管插管时间等是胃肠恶性肿瘤术后老年患者肺部感染的危险因素。结论 老年胃肠恶性肿瘤患者术后发生感染部位以肺部为主,病死率高,对患者的危害性大,针对产生肺部感染的主要危险因素,在患者的术后恢复阶段加强预防,提高患者肺部感染的治愈率。

     

    Abstract: OBJECTIVE To conduct the tracking study of elderly patients with gastrointestinal malignancies undergoing the surgery, analyze the causes of pulmonary infections in the elderly patients during the rehabilitation stage, and put forward the treatment measures so as to reduce the incidence of pulmonary infections. METHODS A total of 75 elderly patients with gastrointestinal malignancies who were hospitalized from Jan 2013 to Dec 2013 were enrolled in the study, then the surgical procedures and postoperative rehabilitation were tracked, the causes and risk factors for the infections were observed, and the prevention measures were formulated. RESULTS Of the 75 elderly patients with gastrointestinal malignancies, 16 had the pulmonary infections, with the infection rate 21.3%. The ratio of the male patients with pulmonary infections to the female patients with pulmonary infections was about 2:1, and there were 10 cases of male and 6 cases of female. Totally 10 patients died of pulmonary infections, with the mortality rate 62.5%. The study concluded that the risk factors for the postoperative pulmonary infections in the elderly patients with gastrointestinal malignancies included the bedridden time, catheter indwelling time, and endotracheal intubation time. CONCLUSION The postoperative pulmonary infections are prevalent in the elderly patients with gastrointestinal malignancies, the mortality rate is high, and the postoperative pulmonary infections may lead to great damage to the patients. It is necessary to strengthen the prevention during the postoperative rehabilitation stage according to the major risk factors for the pulmonary infections so as to raise the cure rate of the patients with pulmonary infections.

     

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