Abstract: OBJECTIVE To investigate and analyze different surgical methods in the treatment of infections for pregnant women with ectopic pregnancy hemorrhagic shock, so as to provide reference for reducing infection rates and complications. METHODS A total of 300 cases of surgery treatment of pregnant patients with ectopic pregnancy hemorrhagic shock in our hospital from Jun. 2013 to Jun. 2015 were randomly chosen. They were divided into two groups, 150 cases were taken with laparoscopic surgery, and 150 patients were taken with laparotomy surgery. The specific type of surgery was determined by the locations of ectopic pregnancy, whether retain the fallopian tubes, and the types of ectopic pregnancy. The specimens collected during the surgery were taken for bacteria culture, identification and susceptibility testing. The patients were taken for incision dressing every day and washed the vulva. RESULTS The infection rates of urinary system of laparoscopic group and laparotomy group were 0% and 4.00%, the surgical wound infection rates were 0 % and 4.67%, and the overall infection rates were 2.00% and 18.67%. Compared to the laparotomy group, the urinary system infection rate, surgical wound infection rate and the overall infection rate of laparoscopic group were significantly reduced. The total number of strains in laparotomy group were 190 cases, in which the constituent ratio of Escherichia coli, Pseudomonas aeruginosa, Enterobacter cloacae were 36.84%, 27.89%, and 10.00%, respectively. The total number of strains in laparoscopic group were 131 cases, in which the constituent ratio of E.coli, P.aeruginosa, E.cloacae were 22.90%, 16.79%, and 15.27%, respectively. Compared to laparotomy group, the E.coli and P. aeruginosas in laparoscopic group were significantly reduced. The susceptibility test results indicated that E.coli, P. aeruginosa, and E.cloacae were highly sensitive to ampicillin/sulbactam, and imipenem. CONCLUSION The urinary system infection rate, surgical wound infection rate and the overall infection rate in laparoscopic group are significantly lower than those of laparotomy group, and it is worthy of promotion.