Abstract: OBJECTIVE To explore clinical predictive factors of ventilator-associated Acinetobacter baumannii pneumonia(AB-VAP)in emergency intensive care unit, so as to improve the prevention consciousness and reduce the infection rate. METHODS Two hundred and forty-three consecutive patients who met the criteria of ventilator-associated pneumonia in emergency intensive care unit from Jul. 2009 to Jun. 2015, were retrospectively evaluated. The data were analyzed by SPSS 18.0. RESULTS The occurrence of AB-VAP was 22.2 %(54 cases)out of 243 cases of patients with ventilator-associated pneumonia. Initial univariate analysis showed that 9 factors were significant,while multivariate stepwise logistic regression analysis indicated that mechanical ventilation no less than 15 days, acute physiology and chronic health evaluation Ⅱ score no less than 21 points, use of glucocorticoid and tracheotomy were independent predictive factors of AB-VAP. CONCLUSION Longer mechanical ventilation, higher acute physiology and chronic health evaluation Ⅱ score, use of glucocorticoid and tracheotomy are independent predictive factors of AB-VAP. AB-VAP may be clinically minimized by shortening duration of mechanical ventilation, improving patients overall situation, reducing usage of glucocorticoid and tracheotomy.