Abstract: OBJECTIVE To investigate the prevalence of pulmonary fungal infections in elderly patients with tuberculosis and analyze the drug resistance so as to provide guidance for clinical treatment. METHODS The clinical data were collected from 207 elderly tuberculosis patients complicated with pulmonary fungal infections who were treated in hospitals from May 2013 to Dec 2015, the specimens were obtained from the enrolled patients, the bacterial culture and isolation were carried out in accordance with 'National Clinical Laboratory Procedures', the drug susceptibility testing was performed on the basis of National Committee for Clinical Laboratory (NCCL) standards, and the distribution and drug resistance of the pathogens causing the pulmonary fungal infections in the elderly patients with tuberculosis were observed. RESULTS Among the specimens that were obtained from the 207 elderly tuberculosis patients complicated with pulmonary fungal infections, the sputum specimens accounted for 87.4%, and fiber bronchoscopes accounted for 8.7%.Of the fungi isolated from the 207 elderly tuberculosis patients complicated with pulmonary fungal infections, the Candida albicans accounted for 60.9%, the Candida tropicalis accounted for 14.0%, and the Candida glabrata accounted for 8.2%.Among the 207 strains of fungi, the drug susceptibility rates to amphotericin B, 5-fluorocytosine, and fluconazole were 100.0%, 97.1%, and 93.7%, respectively; the drug resistance rates to ketoconazole, econazole, and itraconazole were 26.8%, 23.7%, and 7.9%, respectively. CONCLUSION The distribution of the pathogens causing the pulmonary fungal infections in the elderly patients with tuberculosis is relatively complicated.It is necessary to choose sensitive antibiotics on the basis of the results of the drug susceptibility testing so as to raise the clinical cure rate.