Abstract: OBJECTIVE To explore the prevention and control effect of daily check list on pulmonary infections in patients with cerebral infarction, in order to reduce the incidence of pulmonary infections in patients with cerebral infarction. METHODS A total of 118 cases of patients with cerebral infarction treated in our hospital from Jan. 2013 to Dec. 2014 were selected as the observation group, and daily check list was used for intervention. Another 116 patients with cerebral infarction treated in our hospital from Jan. 2011 to Dec.2012 were selected as control group, and routine nursing intervention was adopted. Pulmonary infection rate, nursing quality score and pathogenic bacteria distribution of these two groups were compared after one month of intervention. RESULTS After one month intervention, there were 6 cases got pulmonary infection in observation group, and infection rate was 5.08%, 19 cases in control group with infection rate 16.38%. The difference was significant (P<0.01). Nursing quality score was (9.73±0.18)in observation group,and (7.43±0.26)in control group. The difference was significant (P<0.01). Patients in the observation group were detected 6 strains of pathogenic bacteria, control group 19 strains, and the top three were Escherichia coli, Klebsiella pneumoniae and Staphylococcus epidermidis. There was no significant difference for the amount of pathogenic bacteria detected from the patients in two groups. CONCLUSION Using daily check list for intervention to patients with cerebral infarction can improve patient satisfaction, nurse quality of care and reduce the rate of pulmonary infection.