Abstract: OBJECTIVE To explore the effects of centralized management of cleaning and disinfection of cupping in the disinfection supply center,so as to provide guarantee for safety and convenience of diagnosis and treatment.METHODS A total of 190 used cupping in Mar.2015 were randomly divided into experimental group（150cases）and control group（40cases）.The cupping in control group was taken department dispersed disinfection management style,using chlorine disinfectant for immersion and disinfection,and natural drying.The cupping in experimental group was taken the centralized management style of cleaning and disinfection in the disinfection supply center,using automatic ultrasonic cleaning machine with low foam multiple enzyme detergent for cleaning,disinfection,and drying treatment.Then disposable paper-plastic packaging was used independently,and high pressure steam sterilization was applied.Five cupping in each group were randomly selected for bacterial culture every 3days,and the bacterial qualified rates the two groups of cupping at different time points within 90 dafter disinfection were compared.RESULTS The qualified rates of experimental group were 100%,80.0%,and 20.0% on the1 st,4th,7th day,and 0% after 10 days,and the bacterial count was＞70CFU/piece.The bacteria were not detected in cupping of experimental group within 90 days,with the qualified rate of 100%.The qualified rate of experimental group was significantly higher than that of control group（P＜0.05）.CONCLUSION Using centralized management of cleaning and disinfection of cupping in the disinfection supply center can strengthen the disinfection effect,effectively reduce the hospital infection risks,prolong the storage time,improve the sterile retention rate,also can reduce labor costs,save material resources,so as to meet the requirements of hospital infection control.