降钙素原与内毒素在腹部创伤术后患者肺部感染中的诊断价值

Value of procalcitonin and endotoxin in diagnosis of postoperative pulmonary infections in patients with abdominal trauma

  • 摘要: 目的 分析降钙素原(PCT)与内毒素(ET)在腹部创伤术后患者肺部感染中的诊断价值,为临床诊断提供依据。方法 选取2015年1-12月医院收治的腹部创伤术后肺部感染患者88例,根据感染的病原菌不同将其分组,细菌组30例与非细菌组58例; 对两组患者的血清PCT与ET水平进行检测,并对其进行统计分析。结果 在PCT阳性率与ET阳性率方面,细菌组与非细菌组比较均明显升高,差异均具有统计学意义(P<0.05); PCT在腹部创伤术后患者肺部感染中的诊断敏感度与特异度分别为93.3%、94.8%,ET诊断敏感度与特异度分别为66.7%、69.0%,两者比较差异有统计学意义(P<0.05)。结论 降钙素原与内毒素的检测对腹部创伤术后患者是否并发肺部感染具有较为显著的临床价值,且PCT的诊断价值高于ET,可作为优选诊断指标。

     

    Abstract: OBJECTIVE To analyze the value of procalcitonin (PCT) and endotoxin (ET) in diagnosis of postoperative pulmonary infections in patients with abdominal trauma so as to provide guidance for clinical diagnosis. METHODS A total of 88 abdominal trauma patients complicated with postoperative pulmonary infections who were treated in the hospital from Jan 2015 to Dec 2015 were enrolled in the study and divided into the bacterial group with 30 cases and the non-bacterial group with 58 cases according to the pathogens causing infections.The levels of serum PCT and ET of the two groups of patients were detected, and the statistical analysis was performed. RESULTS The positive rates of PCT and ET were significantly higher in the bacterial group than in the non-bacterial group(P<0.05).The sensitivity and specificity of PCT were respectively 93.3% and 94.8% in the diagnosis of postoperative pulmonary infections in the patients with abdominal trauma; the sensitivity and specificity of ET were respectively 66.7% and 69.0%, and there was significant difference between the two groups(P<0.05). CONCLUSION The detection of PCT and ET has remarkable clinical value in diagnosis of the postoperative pulmonary infections in the patients with abdominal trauma; the PCT has higher diagnostic value than ET, and it can be chosen as the preferred diagnostic indicator.

     

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