Abstract: OBJECTIVE To put forward the strategies to improve the level of control of nosocomial infections in a community health service center via investigation of control and management of nosocomial infections in the community health service center. METHODS The status of control and management of nosocomial infections in 44 community health service centers was supervised and examined on the basis of "Quality Inspection Standards for Hospital Acquired Infections". The information and data were obtained by checking document and observing onsite. RESULTS The framework of management of nosocomil infections has been established in all of the community health service centers, however, the personnel structure of the staff was unreasonable, the meetings lacked of substantive contents. Although the related nosocomial infection systems have been established, they have not been updated according to the new standards in a timely manner and have not been implemented well. The consciousness of microbial submission of infection cases was not strong, the use of antibiotics remained experience-directed. The division was unreasonable in 45.5% of the key departments, the potential safety hazards existed in the disinfection and isolation. The management of nosocomial infection lacked sustained improvement. CONCLUSION The nosocomial infection management system has been established in the community health service centers, however, the role of management fails to give full play, the implementation of the systems lacks the continuous improvement, and the use of antibiotics lacks the effective management. It is necessary to give play to the role of the tertiary or secondary general hospitals and strengthen the training and guidance of the grass-roots infection control personnel so as to improve the level of management of nosocomial infection.