Abstract: OBJECTIVE To improve the implementation of respiratory tract management measures of medical staffs, patients and their families during perioperative period through early-warning scales of pulmonary infection, in order to reduce incidence of postoperative pulmonary infection. METHODS A total of 3918 patients who did not use the early-warning scales of postoperative pulmonary infection from Jan.2015 to Aug.2015 were selected as control group, and 3863 patients who used the early-warning scales of postoperative pulmonary infection from Sep.2015 to Apr. 2016 were selected as experimental group. The infection rates of the two groups were compared. RESULTS Medical workers' awareness of preventing perioperative pulmonary infection was strengthened after the implementation of the early-warning scales of postoperative pulmonary infection. The qualified rate of perioperative respiratory tract management measures increased from 51.7% to 73.5%, while the incidence of pulmonary infection was decreased from 1.42% to 0.62%, which showed statistical significance compared with the initial data (P<0.05). CONCLUSION An early-warning scale of postoperative pulmonary infection can efficiently prevent the occurrence of postoperative pulmonary infection as well as improve nursing quality in perioperative period, so it is worth popularizing and applying.