Abstract: OBJECTIVE To compare and analyze the CT manifestations of three kinds of pulmonary fungal infections (pulmonary candidiasis, invasive pulmonary aspergillosis, pulmonary cryptococcosis), so as to provide evidence for clinical treatment. METHODS The clinical data of 82 patients with pulmonary fungal infection diagnosed from Jul. 2011 to Jul. 2015 were retrospectively analyzed, including 21 cases of pulmonary candidiasis, 41 cases of invasive pulmonary aspergillosis (IPA), and 20 cases of pulmonary cryptococcosis. The CT manifestations of three kinds of common pulmonary fungal infections were compared. RESULTS Simple lesions in patients with pulmonary cryptococcosis were significantly higher than those of pulmonary candidiasis and IPA patients (P<0.05), the occurrence rates of gathered nodular and air bronchus syndrome in patients with pulmonary cryptococcosis were significantly higher than those of pulmonary candidiasis and IPA patients (P<0.05), and voids occurrence rate in patients with IPA was higher than that of pulmonary candidiasis and pulmonary cryptococcosis patients (P<0.05). CONCLUSION Pulmonary cryptococcosis nodules have the characters of aggregated distribution and air bronchogram, while the IPA nodules are hollow, especially the characteristics of air crescent sign, and pulmonary candidiasis has the highest incidence of ground glass shadow.