Abstract: OBJECTIVE To analyze and evaluate the effect of artificial bone surface covered with oral restorations membrane on prevention of postoperative implant cavity infections, so as to provide a reference basis for clinical treatment. METHODS A total of 72 patients with jaw cystic defect for artificial bone implantation from Mar. 2012 to Mar. 2016 in our hospital were selected, and were divided into observation group and control group according to the random number table method, with 36 cases in each group. Patients in control group were given routine treatment, and in observation group were given artificial bone surface covered oral restorations membrane. The postoperative femoral cavity infection rates between the two groups were compared. RESULTS Observation group occurred 2 cases of postoperative infection, with the infection rate of 5.56%, and control group occurred 8 cases of infections, with the infection rate of 22.22%. Compared with control group, the infection rate of observation group was significantly lower (P<0.05). CONCLUSION Oral restorations membrane covered with artificial bone for patients with jaw cystic defect and artificial implantation can effectively prevent the occurrence of bone implant infections, reduce the incidence of bone implant cavity infections, also can guide the implant bone tissue regeneration, and thus can be further popularized and applied in clinic.