Abstract: OBJECTIVE To study the impact of maintenance of mean arterial pressure on the renal function and renal blood flow indexes of patients with infectious shock in ICU,so as to understand the intervention significance of maintaining mean arterial pressure. METHODS A total of 75 patients with infectious shock in ICU of our hospital from Mar. 2014 to Jun. 2016 were selected as observation group,another 75 healthy persons at the same time were selected as control group,then the renal function and renal blood flow indexes of the two groups were detected and compared,and the renal function and renal blood flow indexes of observation group with different level of maintenance mean arterial pressure were compared too. RESULTS The renal function indexes including Scr,CysC and BUN of observation group were respectively (240.53±25.57)μmol/L,(2.41±0.37)mg/L and(35.36±3.17)mg/dl,which were all higher than (198.25±17.25)μmol/L,(1.57±0.20)mg/L and(23.23±2.60)mg/dl of control group,the renal main artery and interlobar artery Vm,Vd and PI of observation group were respectively (40.23±3.84)cm/s,(18.45±2.24)cm/s,(1.38±0.17) and(17.67±1.80)cm/s,(10.61±1.52)cm/s,(1.25±0.16),which were all lower than the(50.87±4.66)cm/s,(25.20±2.63)cm/s,(1.05±0.11)and(14.24±1.81)cm/s,(25.26±2.63)cm/s,(0.85±0.11)of control group, and the renal blood flow indexes of observation group with higher mean arterial pressure were all worse than those of patients with lower mean arterial pressure,and the differences were statistically significant (all P＜0.05). CONCLUSION The impact of maintaining mean arterial pressure on the renal function and renal blood flow indexes of patients with infectious shock in ICU is great,so the mean arterial pressure regulation and improvement of these patients should be paid more attention.