Abstract: OBJECTIV To explore the construction of the management process of inhaled pulmonary infection in hospitalized medical patients, so as to reduce the incidence of pulmonary infection. METHODS A total of 158 cases of hospitalized medical patients from Jan. 2012 to Dec. 2015 were selected, and were divided into observation group (from Jan. 2014 to Dec. 2015, the modified intervention management process) and control group (from Jan. 2012 to Dec.2013, the traditional management process) according to the time of admission. The inhaled pulmonary infection rate, causes, satisfaction indexes, adverse complications and satisfaction rate of intervention of the two groups of patients were compared. RESULTS The inhaled pulmonary infection rate of observation group and control group were respectively 11.76% and 37.78%, and the difference was significant (P<0.05). The ventilator time, pulmonary rales disappeared time, ICU stay time and total hospitalization time of observation group were significantly lower than those of control group (P<0.05) The causes of pulmonary infection of observation group included gastrointestinal dysfunction (5.88%), sputum improper (2.94%), and inappropriate suctioning method (2.94%), and the causes of pulmonary infection of control group included gastrointestinal dysfunction (10%), improper nasal feeding methods(3.33%), improper suctioning method (13.33%), improper position management of severe(2.22%), and severe cough (8.89%)., The adverse complications and satisfaction rate of intervention of 68 cases in observation group were 19.12% and 95.59%, and of 90 cases in control group were 38.89% and 70%. CONCLUSION The improved intervention management process can reduce the risk of pulmonary infection in hospitalized medical patients, and improve satisfaction of patients.