急诊ICU肺部感染患者的临床特点及预防分析

Clinical characteristics of patients with pulmonary infection in ICU of emergency department and prevention countermeasures

  • 摘要: 目的 探讨急诊ICU老年患者肺部感染的临床特点及相关危险因素,并针对高危因素分析其预防对策。方法 选取2013年2月-2016年2月医院急诊ICU收治的老年患者866例,研究老年患者肺部感染的临床特征及感染病原菌分布,采用单因素与多因素分析导致ICU老年患者肺部感染的高危因素,并进行统计学检验。结果 肺部感染患者的主要临床表现是咳嗽咳痰、胸闷气促,其中98.88%的患者X线检查发现阳性征象,痰培养结果显示,肺炎克雷伯菌和铜绿假单胞菌构成比相对较高,分别占39.32%和30.34%; 单因素分析结果显示,年龄、基础疾病、侵入性操作与老年患者肺部感染的发生具有相关性(P<0.05); 多因素logistic回归分析结果显示,年龄≥80岁、基础疾病≥2种、有侵入性操作是导致肺部感染的独立危险因素; 89例肺部感染患者经过治疗,其中48例(53.93%)患者症状完全消失,17例(19.10%)患者症状缓解,18例(20.22%)患者病情恶化,6例(6.74%)患者死亡。结论 ICU老年患者肺部感染的高危因素包括年龄≥80岁、有≥2种基础疾病以及侵入性操作,针对以上高危因素制定预防措施对于减少肺部感染具有积极作用。

     

    Abstract: OBJECTIVE To explore the clinical characteristics of pulmonary infections in elderly patients in ICU of emergency department, analyze the related risk factors, and take the prevention countermeasures according to the high-risk factors.METHODS A total of 866 elderly patients who were treated in the ICU of emergency department from Feb 2013 to Feb 2016 were enrolled in the study.The clinical characteristics of pulmonary infections in the elderly patients and distribution of pathogens causing the infections were observed, the high-risk factors for the pulmonary infections in the elderly patients of ICU were analyzed by means of univariate analysis and multivariate analysis, and the statistical analysis was performed.RESULTS Cough and expectoration, chest tightness and shortness of breath were the major clinical manifestations of the patients with pulmonary infections.The X-ray examination showed that 98.88% of the patients had positive signs.The result of sputum culture indicated that the constituent ratios of Klebsiella pneumoniae and Pseudomonas aeruginosa were 39.32% and 30.34%, respectively.The result of the univariate analysis revealed that the incidence of pulmonary infections in the elderly patients was associated with the age, underlying diseases, and invasive operations (P<0.05).The result of the multivariate logistic regression analysis showed that the no less than 80 years of age, no less than 2 types of underlying diseases, and invasive operations were the independent risk factors for the pulmonary infections. Among 89 patients with pulmonary infections, there were 48 (53.93%) patients whose symptoms completely disappeared, 17 (19.10%) patients whose symptoms relieved, 18 (20.22%) patients whose condition deteriorated, and 6 (6.74%) patients who died after the treatment.CONCLUSIONThe high-risk factors for the pulmonary infections in the elderly patients of ICU include the no less than 80 years of age, no less than 2 types of antibiotics, and invasive operations.It plays a positive role to develop the prevention measures according to the above high-risk factors so as to reduce the incidence of pulmonary infections.

     

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