Abstract: OBJECTIVE To investigate the effect of visual management program on nosocomial infections in hospitalized schizophrenic patients. METHODS A total of 796 schizophrenic patients with the implementation of visual management program from Jan. 2015 to Dec. 2016 were enrolled and set as observation group, and 761 cases of schizophrenia patients without the implementation of visual management program from Jan. 2013 to Dec. 2014 were set as control group. Patients in control group were managed with routine care and nosocomial infection control measures, and in observation group were treated with visual management program. The case number of nosocomial infections and the incidence of nosocomial infections were calculated. Patients with nosocomial infections were sampled for identification of pathogens. The compliance rate of hand hygiene compliance, equipment quality inspection, environmental sanitation inspection, rational use of antimicrobial agents, aseptic operation and nosocomial infection management quality were statistically analyzed. RESULTS There were 36 cases of nosocomial infections in control group, with the infection rate of 4.73%, and 19 cases in observation group, with the infection rate of 2.39%. The nosocomial infection rate in observation group was significantly lower than that in control group (P＜0.05). Sixty-two strains of pathogens were isolated from 55 schizophrenic patients, among which 43 strains (69.35%) were gram-negative bacteria, 17 strains (27.42%) were gram-positive bacteria, and 2 strains (3.23%) were fungi. The quality of nosocomial infection management in observation group was (85.25±3.50) point, which was significantly higher than (66.50±2.15) point in control group (P<0.05). After the implementation of visual management, the compliance rate of hand hygiene compliance, equipment quality inspection, environmental sanitation inspection, antimicrobial rational use and aseptic operation of observation group were significantly improved (P<0.05). CONCLUSION Visual management is a very effective management method to improve the quality of nosocomial infection management and reduce the incidence of nosocomial infections.