Abstract:
OBJECTIVE To detect procalcitonin (PCT) in patients with cerebral hemorrhage complicated with infection and study its value in prognostic evaluation.
METHODS A total of 120 cases of patients with cerebral hemorrhage from Aug. 2014 to Sep. 2016 were selected and divided into patients with infection (infection group, 50 cases) and patients without infection (non-infection group, 70 cases). The differences of serum PCT between infection group and non-infection group at 1d, 3d, 5d and 7d after admission to ICU were compared. The differences of PCT between dead patients and survival patients in infection group were analyzed. The sensitivity and specificity of PCT in the death prediction for patients with intracerebral hemorrhage complicated with infection were analyzed.
RESULTS The PCT at 1d, 3d, 5d and 7d after admission to ICU in infection group were (3.18±1.04), (5.72±1.54), (4.92±1.36) and (2.21±0.95)ng/ml, which were significantly higher than those in non-infection group (All
P<0.05). The PCT at 1d, 3d, 5d and 7d after admission to ICU in death patients were (3.40±1.02), (7.11±1.50), (6.81±1.25) and (4.01±0.91)ng/ml, which were significantly higher than those in survival patients (
P<0.05). The critical value of PCT in the death prediction for patients with intracerebral hemorrhage complicated with infection was 6.50 ng/ml, and the sensitivity and specificity were 0.620 and 0.840 respectively.
CONCLUSION PCT levels are significantly increased in patients with cerebral hemorrhage complicated with infection, and serum PCT is of great value in predicting the death of cerebral hemorrhage complicated with infection.