金屏汤加减治疗小儿反复呼吸道感染的疗效及对免疫能力的调节作用

Effect of Jinping decoction on recurrent respiratory tract infection and immunity in children

  • 摘要: 目的 评价金屏汤加减治疗小儿反复呼吸道感染的临床疗效及对免疫能力的调节作用。方法 将2017年1月-2018年12月海口市妇女儿童医院收治的146例反复呼吸道感染患儿分为对照组(n=73例)和研究组(n=73例),对照组患儿采用西药常规治疗,并口服匹多莫德颗粒以调节免疫力。研究组在对照组治疗的基础上,口服金屏汤。比较两组患儿治疗前后中医症候积分和治疗疗效,比较两组患儿临床症状消失时间,比较两组患儿治疗前后血清免疫球蛋白(IgG、IgA、IgM)水平。结果 研究组治疗后纳差、面色少华、大便不调和自汗乏力症候积分低于对照组(P<0.05);研究组治疗总有效率为91.78%高于对照组79.45%(P<0.05);研究组患儿临床症状消失时间早于对照组(P<0.05);研究组治疗后免疫功能指标IgA、IgG和IgM水平高于对照组(P<0.05);研究组患儿发病次数改善和病情改善情况优于对照组(P<0.05)。结论 金屏汤辅助治疗小儿反复呼吸道感染效果确切,可有效改善临床症状,并提高机体免疫力,减少患儿发病次数,缩短病程,疗效显著,值得临床进一步研究。

     

    Abstract: OBJECTIVE To evaluate the clinical effect of Jinping decoction on recurrent respiratory tract infection and immunity in children. METHODS Total of 146 children with recurrent respiratory tract infection admitted to Haikou women's and children's Hospital from Jan. 2017 to Dec. 2018 were divided into the control group and study group, 73 cases in each group. The control group was treated with routine western medicine and oral pidotimod to regulate immunity. On the basis of the therapy in the control group, the study group was given Jinping Decoction orally. TCM symptom score, therapeutic effect, the disappearance time of clinical symptoms, serum immunoglobulin(IgG, IgA, IgM) levels were compared between the two groups before and after the treatment. RESULTS The scores of anorexia, complexion, dysuria, spontaneous sweating and fatigue in the study group were significantly lower than that in the control group(P<0.05); the effective rate in the study group was 91.78%, which was significantly higher than that of 79.45% in the control group(P<0.05). The clinical symptoms subsided earlier significantly in the study group than that in the control group(P<0.05). Immune function indexes such as IgA, IgG and IgM in the study group were significantly higher than that in the control group after the treatment(P<0.05). The improvement of incidence and condition in the study group was significantly better than that in the control group(P<0.05). CONCLUSION Jinping decoction is effective in the treatment of children with recurrent respiratory tract infection. It can effectively improve the clinical symptoms, improve the body immunity, reduce the incidence of children, shorten the course of disease, and should be worthy of further clinical research.

     

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