Abstract:
OBJECTIVE To explore the risk factors for postoperative urinary tract infection in women with perimenopausal stress urinary incontinence(SUI) undergoing midurethral suspension(MUS) surgery and analyze the characteristics of urodynamics.
METHODS A total of 334 patients who underwent MUS surgery due to SUI in urology department of Ningbo Yinzhou No. 2 Hospital from Jan 2019 to Dec 2021 were recruited as the study subjects and divided into the urinary tract infection group with 32 cases and the non-urinary tract infection group with 302 cases according to the status of postoperative urinary tract infection. The clinical data were collected from the patients. The three urodynamics parameters abdominal leak point pressure, detrusor contractility and residual urine volume were evaluated by GBS002 type multi-channel urodynamic examination instrument.
RESULTS There were significant differences in the previous history of urinary tract surgery, severity of SUI and complication with diabetes mellitus between the two groups(
P<0.05). The result of multivariate logistic regression analysis showed that the previous history of urinary tract surgery, severity of SUI and complication with diabetes mellitus were the risk factors for postoperative urinary tract infection in the SUI patients undergoing MUS(
P<0.05). The abdominal leak point pressure and detrusor contractility of the urinary tract infection group were significantly lower than those of the non-urinary tract infection group, while the residual urine volume level of the urinary tract infection group was significantly higher than that of the non-urinary tract infection group(
P<0.05). The result of receiver operating characteristic(ROC) curve analysis showed that the areas under curves(AUCs) of the urodynamics indexes abdominal leak point pressure, detrusor contractility and residual urine volume were respectively 0.753, 0.749 and 0.772 in predication and diagnosis of urinary tract infection, while the AUC of the joint detection of the three indexes was 0.853, with the value of prediction and diagnosis the highest.
CONCLUSION The previous history of urinary tract surgery, severity of SUI and complication with diabetes mellitus are the independent risk factors for the postoperative urinary tract infection in the SUI patients undergoing MUS, and the joint detection of urodynamics indexes has certain value in prediction and diagnosis of urinary tract infection.