Abstract: OBJECTIVE To explore the pathogenic bacterial distribution characteristics and susceptibility factors of urinary tract infection in patients with urinary tract infection after cervical cancer surgery. METHODS A total of 200 patients who underwent cervical cancer surgery in Wuhan Third Hospital from Oct 2019 to Oct 2022 were retrospectively recruited as the research subject. According to whether postoperative urinary tract infection occurred, they were divided into the infection group (43 cases) and the non-infection group (157 cases). The status of urinary tract infection and distribution characteristics of pathogenic bacteria in patients with cervical cancer after surgery were analyzed, and the predisposing factors of urinary tract infection in patients with cervical cancer after surgery was analyzed by univariate and multivariate analysis. RESULTS There were 43 cases of urinary tract infection in 200 patients with cervical cancer after operation, and the incidence was 21.50%. A total of 43 strains of pathogenic bacteria were isolated from patients in the infection group, including 28 strains (65.12%) of gram-negative bacteria and 15 strains (34.88%) of gram-positive bacteria. Long hospital stay, transurethral indwelling catheter, postoperative urinary retention and high levels of procalcitonin (PCT) were the risk factors for urinary tract infection in patients with cervical cancer after surgery (OR=4.121, 7.531, 6.508, 7.561, P＜0.05). CONCLUSION The incidence of urinary tract infection in patients after cervical cancer surgery is high, and gram-negative bacteria are the main pathogens. Long hospital stay, transurethral indwelling catheter, postoperative urinary retention and high levels of PCT are susceptibility factors of urinary tract infection in patients after cervical cancer surgery.