OBJECTIVE To statistically analyze the data of herpes zoster vaccination in the past four years and summarize the current status of herpes zoster vaccination.

METHODS The data of herpes zoster vaccination were collected from the Fifth Medical Center of PLA General Hospital between 2020 and 2023. The descriptive statistical analysis was performed for the status vaccination regarding to the age group and gender. The influencing factors for the vaccination were analyzed, and the questionnaire survey was conducted for adverse reactions after the vaccination.

RESULTS A total of 495 people received herpes zoster vaccination in the hospital from 2020 to 2023, including 290 female and 205 male, and the overall number of vaccination showed an upward trend. Among the populations who received the vaccination, the proportion of the population aged between 50 and 60 years old was 47.68%, the population aged between 60 and 70 years old 39.19%, the population aged more than 70 years old 13.13%. Totally 353 cases had the previous history of herpes zoster virus infection, accounting for 71.31%. The major adverse reactions for the herpes zoster vaccination included slight swelling, pruritus, fatigue and headache with low-grade fever. The follow-up result showed that 4 of 376 vaccination people reported to be reinfected with herpes zoster virus.

CONCLUSIONS The people aged between 50 and 60 years old are the major population for herpes zoster vaccination, the vaccination rate declines year by year among the population aged more than 60 years old, and the rate of willing to vaccination is low. It is necessary for the epidemic prevention institutions to actively disseminate the knowledge of herpes zoster vaccine and carry out health education, especially the vulnerability to the virus and safety of the vaccine, so as to raise the public′s willingness to the vaccination.