OBJECTIVE  The aim was to clarify the construction of antibiotic stewardship programs, the status of management strategies and barriers in medical institutions of Shaanxi Province.

METHODS  Referring to the Clinical Application of Antibacterial Drugs Guiding Principles (2015) and the American Checklist for Core Elements of Hospital Antibiotic Stewardship Programs, an online survey designed by Wenjuanxing was used from Oct. to Nov. in 2022, and were send to personnels of antibiotic management and clinical pharmacist by the APP WeChat.

RESULTS  Totally 58 hospitals involved in the survey, all of which basically meet the requirements of antibacterial drug management in China; but there were still gaps with the requirements of the U. S. Checklist for Core Elements. The antibiotic stewardship programs team was mainly composed of clinical pharmacists and physician in infectious department, and the antimicrobial prescription review system were comprehensive and fully implemented. In terms of intervention strategies to optimize the use of antibiotics, 37.93% of the hospitals implemented the pre-review for antibiotics prescription; the common interventions included preoperative prophylactic antibiotic use (86.21%) and community-acquired pneumonia (72.41%). The main impeding factors for antimicrobial managements were lack of specialists and teams in infection (62.07%), insufficient financial investment (67.24%), doctors′ refusal to change their prescribing habits (53.45%), lack of supports from leadership (55.17%), and low priority of antimicrobial drug management (48.28%).

CONCLUSIONS  The AMS system in Shaanxi Province is relatively complete and paid attention generally, but mostly by the administrative personnel. Future research and strategy development should consider how to overcome the barriers and improve scientific antimicrobial drug management.