OBJECTIVE To evaluate the changes in monitoring indicators related to healthcare-associated infections (HAIs) management in Anhui Province in 2018 and 2022, to provide a scientific basis for optimizing HAI control strategies.

METHODS A cross-sectional survey was conducted in 2019 and 2023 across 48 secondary and tertiary medical institutions, HAI data were collected and analyzed.

RESULTS The two-year averages of monitoring indicators were as follows: the incidence rate of HAIs was 0.66%, the prevalence rate of HAIs was 1.69%, the incidence rate of surgical site infection for class Ⅰ incisions was 0.20%, the antibiotic usage rate was 44.59%, the pathogen detection rate for therapeutic antibiotics was 43.76%, the incidence rate of catheter-related bloodstream infection (CRBSI) was 0.64‰, the incidence rate of ventilator-associated pneumonia (VAP) was 5.81‰, and the incidence rate of catheter-associated urinary tract infection (CAUTI) was 0.79‰. By 2022, significant improvements were observed in most indicators (P < 0.05). Compared to tertiary hospitals, secondary hospitals exhibited low rates of hospital infection incidence, prevalence, class Ⅰ incision infections, antibiotic utilization and CRBSI, but high rates of VAP and CAUTI (P < 0.05).

CONCLUSIONS Significant improvements have been made in monitoring indicators related to HAI managements in Anhui Province. However, secondary hospitals still need to enhance their capabilities of monitoring indicators and detecting pathogens.