过氧化氢消毒剂对病房终末消毒的效果评价

Evaluation of effect of hydrogen peroxide disinfectant on terminal disinfection in wards

    摘要
  • 摘要:
    目的 探讨过氧化氢消毒剂对医疗机构病房终末消毒的效果。
    方法 2024年4-6月在南昌大学第一附属医院公卫中心出院患者病房内分别使用0.5%浓度(低浓度)和5%浓度(高浓度)过氧化氢消毒湿巾对患者高频接触物表进行消毒，消毒前后共随机采样180份，并检测样本病原菌；同年7-8月在公卫中心出院患者病房内使用过氧化氢干雾消毒器对其进行空气消毒，消毒前后分别采样90份，以嗜热脂肪地芽孢杆菌作为生物指示剂，布于空气消毒病房各点位以评估其消毒水平。对比环境采样结果并分析细菌分布情况。
    结果 低浓度和高浓度过氧化氢消毒湿巾对病房物表消毒合格率分别为95.56%(86/90)和98.89%(89/90)，消毒效果无统计学差异；消毒前不合格样本检出病原菌120株，以革兰阴性菌(69.17%)为主，多重耐药菌检出率为22.50%(27/120)，消毒后仅检测出1株耐碳青霉烯类鲍曼不动杆菌；7.5%过氧化氢干雾消毒器对出院患者病房内空气消毒合格率为96.00%，消毒后平均空气菌落数为2 CFU/(5 min·皿)，空气消毒对嗜热脂肪地芽孢杆菌片的杀灭率为100.00%。
    结论 过氧化氢消毒剂能满足医疗机构病房内终末消毒要求，使用便携高效。

     

    Abstract:
    OBJECTIVE To explore the effect of hydrogen peroxide disinfectant on terminal disinfection in wards of medical institutions.
    METHODS The surfaces of highly frequent contact objects of the wards of the First Affiliated Hospital of Nanchang University from which the public health center patients were discharged between Apr. 2024 and Jun. 2024 were respectively disinfected with 0.5% (low) and 5% (high) concentrations of hydrogen peroxide disinfecting wipes, totally 180 samples were randomly collected before and after the disinfection, and the pathogens were detected. The air of the wards from which the public health center patients were discharged between Jul. 2024 and Aug. 2024 were disinfected with hydrogen peroxide dry mist disinfection device, and 90 samples were respectively collected before and after the disinfection. Geobacillus stearothermophilus was used as the biological indicator and placed at various points within the air-disinfected wards to evaluate the disinfection level. The environmental sampling results and distribution of bacteria were observed and compared.
    RESULTS The qualified rates of disinfection of the object surfaces were 95.56%(86/90) and 98.89%(89/90) respectively for the low and high concentratioins of hydrogen peroxide disinfecting wipes, and there was no significant difference in the disinfection effect. Totally 120 strains of pathogens were isolated from unqualified samples before the disinfection, among which gram-negative bacteria (69.17%) were dominant, and the isolation rate of multidrug-resistant organisms was 22.50%(27/120); only 1 strain of carbapenem-resistant Acinetobacter baumannii was isolated after the disinfection. The qualified rate of disinfection of air in the wards was 96.00% by 7.5% hydrogen peroxide dry mist disinfection device, the average bacterial colony counts in the air were 2 CFU/(5 min·vsl) after the disinfection, and the killing rate of Geobacillus stearothermophilus was 100.00% by the air disinfection.
    CONCLUSION The hydrogen peroxide disinfectant can meet the requirement for terminal disinfection of the wards of the medical institutions, and it is portable and highly efficient.

     

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