Abstract: Pathogenic microorganisms in the air mostly adhere to the surfaces of particles and spread, causing various infectious diseases and posing a threat to human health. Adopting appropriate disinfection methods for indoor air and strictly adhering to air quality standards for disinfection can effectively prevent the transmission of infectious diseases by pathogenic microorganisms, thereby protecting human health and improving quality of life. This paper reviews the mechanisms of action, research status, and characteristics of commonly used indoor air disinfection methods from three aspects: physical, chemical and other aspects. It also discusses the future development trends of indoor air disinfection methods.