2018-2023年无锡地区5岁以下儿童病毒性腹泻监测报告

Surveillance report of viral diarrhea in children under 5 years old in Wuxi from 2018 to 2023

  • 摘要:
    目的 监测无锡地区<5岁儿童病毒性腹泻感染的常见病原体,以分析其流行特征及趋势。
    方法 采集2018-2023年无锡地区哨点医院的住院儿童腹泻标本和门诊儿童腹泻标本,使用实时荧光定量聚合酶链反应(PCR)对标本分别进行诺如病毒、轮状病毒、札如病毒、肠道腺病毒和星状病毒的核酸检测,并对监测结果进行统计学分析。
    结果 1 898份腹泻标本共检出病毒阳性病例654份,总检出率为34.46%,其中以诺如病毒和轮状病毒的检出率最高,分别为12.54%和11.70%。在12~<24月龄腹泻儿童中病毒的检出率最高,达到59.03%。住院腹泻儿童中以轮状病毒的检出率最高,为14.03%;门诊腹泻儿童中以诺如病毒的检出率最高,为11.93%。轮状病毒在住院儿童和门诊儿童中的检出率差异具有统计学意义(P<0.05)。
    结论 病毒性腹泻病在无锡地区12~<24月龄儿童中的感染率非常高,提示需进一步优化该年龄段儿童腹泻病的防控措施。

     

    Abstract:
    OBJECTIVE To monitor the common pathogens for viral diarrhea in children under 5 years old in Wuxi area, and to analyze their epidemiological characteristics and trends.
    METHODS Diarrhea specimens were collected from inpatient and outpatient children with diarrhea in sentinel hospitals in Wuxi from 2018 to 2023. The norovirus, rotavirus, sapovirus, enteradenovirus and astrovirus were detected by Real-time fluorescence quantitative polymerase chain reaction (PCR), and the monitoring results were statistically analyzed.
    RESULTS A total of 654 virus-positive cases were detected from 1898 diarrhea specimens with an overall detection rate of 34.46%. Among them, norovirus and rotavirus had the highest detection rates 12.54% and 11.70%, respectively. The detection rate of viruses was the highest in children aged 12 to < 24 months, reaching 59.03%. In inpatient children with diarrhea, rotavirus had the highest detection rate at 14.03%, while in outpatient children with diarrhea, norovirus had the highest detection rate at 11.93%. There was a significant difference in the detection rate of rotavirus between inpatient and outpatient children (P < 0.05).
    CONCLUSION Viral diarrheal diseases exhibit a notably high detection rate among children aged 12 to < 24 months in Wuxi, suggesting the need to further optimize prevention and control measures for this age group.

     

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