2014-2023年陕西省多重耐药菌检出变化趋势及其与全国平均水平比较

Changing trends of isolation rates of multidrug-resistant organisms in Shaanxi Province from 2014 to 2023 and comparison with national average levels

    摘要
  • 摘要:
    目的 了解陕西省2014-2023年多重耐药菌检出变化情况，为制定耐药菌防控及监测提供理论依据。
    方法 应用WHONET 5.6软件对陕西省耐药监测网入网单位2014-2023年10年检测的多重耐药菌数据进行分析，同时与公布的全国平均水平进行比较。
    结果 2014-2023年多重耐药菌检出率多数呈下降趋势(均P＜0.05)。甲氧西林耐药金黄色葡萄球菌(MRSA)检出率从45.7%降至35.8%，甲氧西林耐药凝固酶阴性葡萄球菌(MRSCN)检出率从81.8%降至75.8%，均高于全国平均水平。万古霉素耐药屎肠球菌(VREfm) 检出率3.1%降至0.5%，万古霉素耐药粪肠球菌(VREfa)检出率从1.7%降至0%，与同年全国平均水平持平或略低。肺炎链球菌中红霉素耐药肺炎链球菌(ERSP)检出率高于青霉素耐药肺炎链球菌(PRSP)，PRSP检出率呈下降趋势(从8.0%降至0.8%)，ERSP检出率略有上升(96.2%升至98%)，比同年全国平均水平略高。碳青霉烯类耐药大肠埃希菌(CR-ECO)检出率呈下降趋势(2.3%降至1.0%)，碳青霉烯类耐药肺炎克雷伯菌(CR-KPN)检出率呈波动状略有上升趋势(6.1%升至8.2%)，略低于全国平均水平。碳青霉烯耐药鲍曼不动杆菌(CR-ABA)和碳青霉烯耐药铜绿假单胞菌(CR-PAE)检出率呈下降趋势(CR-ABA检出率从66.2%降至60.3%，CR-PAE检出率从32.6%降至19.7%)，略高于全国平均水平。
    结论 陕西省2014-2023年多重耐药菌检出率除ERSP和CR-KPN外，呈下降趋势；VRE和CRE检出率低于全国平均水平，其他略高于全国平均水平。

     

    Abstract:
    OBJECTIVE To investigate the changes of isolation rates of multidrug-resistant organisms (MDROs) in Shaanxi Province from 2014 to 2023 so as to provide theoretical bases for prevention, control and surveillance of drug-resistant organisms.
    METHODS The data of MDROs that were detected by the networked units of Shaanxi Antimicrobial Resistance Surveillance System in 10 years from 2014 to 2023 were analyzed by WHONET 5.6 software and were compared with the national average levels.
    RESULTS The isolation rates of MDROs generally showed downward trends from 2014 to 2023 (all P < 0.05). The isolation rate of methicillin-resistant Staphylococcus aureus (MRSA) dropped from 45.7% to 35.8%, and that of methicillin-resistant coagulase-negative Staphylococcus (MRCNS) decreased from 81.8% to 75.8%, higher than the national average levels. The isolation rate of vancomycin-resistant Enterococcus faecium (VREfm) dropped from 3.1% to 0.5%, and that of vancomycin-resistant Enterococcus faecalis (VREfa) declined from 1.7% to 0, equal to or slightly lower than the national average levels. Among the Streptococcus pneumoniae strains, the isolation rate of erythromycin-resistant S. pneumoniae (ERSP) was higher than that of the penicillin-resistant S. pneumoniae (PRSP), the isolation rate of PRSP showed a downward trend (from 8.0% to 0.8%), while the isolation rate of ERSP rose slightly (from 96.2% to 98%), slightly higher than the national average levels. The isolation rate of carbapenem-resistant Escherichia coli (CR-ECO) showed a downward trend (from 2.3% to 1.0%), the isolation rate of carbapenem-resistant Klebsiella pneumoniae (CR-KPN) fluctuated and showed slightly rising trend (from 6.1% to 8.2%), slightly lower than the national average levels. The isolation rates of carbapenem-resistant Acinetobacter baumannii (CR-ABA) and carbapenem-resistant Pseudomonas aeruginosa (CR-PAE) strains showed downward trends (with CR-ABA decreasing from 66.2% to 60.3%, CR-PAE declining from 32.6% to 19.7%), slightly higher than the national average levels.
    CONCLUSIONS The isolation rates of the MDROs showed downward trends in Shaanxi Province from 2014 to 2023 except for ERSP and CRKP. The isolation rates of VRE and CRE are lower than the national average levels, while the isolation rates of other MDROs are slightly higher than the national average levels.

     

    • HTML全文
    • 参考文献(25)
    • 相关文章
    • 施引文献
  • 资源附件(0)

/

返回文章
返回
下载中心