不同系统手术后肺炎的临床特征及其发生的时间分布

Clinical characteristics of postoperative pneumonia patients undergoing different types of surgeries and distribution of onset time

  • 摘要:
    目的 探索不同手术患者术后肺炎的窗口期, 为优化感染监测与防控策略提供循证参考。
    方法 回顾性收集2019年1月-2024年12月4所不同类型医疗机构263例术后肺炎患者的社会人口学特征、临床与手术等相关信息, 分析不同手术患者术后肺炎的时间窗。
    结果 社会人口学与基础疾病的术后肺炎时间窗组间差异无统计学意义, 手术类别、切口类别、手术入路、手术时长等患者的术后肺炎时间窗差异有统计学意义(P<0.05)。263例患者发生术后肺炎的平均时间为2.00(1.00, 7.00)d, 不同系统手术的术后时间窗不同, 其中神经系统手术后0 d(16例)和第1天(17例)为发病峰值, 消化系统与骨科手术后第1天单日峰值;皮肤手术后肺炎发病时间跨度较大(术后0~53 d), 无明确高峰。33.33%的心血管系统手术病例在术后10 d发病。术后肺炎的诊断要素同样存在显著的时间差异, 发热与血常规白细胞异常出现时间较早, 出现时间中位数为4.00 d, 肺部影像学改变出现的较晚, 出现时间中位数为7.00 d。
    结论 术后肺炎发病具有显著的时间差异, 并证实了术后肺炎诊断要素显著的时空异质性, 为制定手术类型导向的动态术后肺炎监测方案与防控措施提供了量化依据。

     

    Abstract:
    OBJECTIVE To explore the time windows for postoperative pneumonia in patients undergoing different surgeries, providing evidence-based references for optimizing infection monitoring and prevention and control strategies.
    METHODS Sociodemographic characteristics, clinical information and surgical details of 263 patients with postoperative pneumonia from four different types of medical institutions between Jan. 2019 and Dec. 2024 were retrospectively collected. The time windows for postoperative pneumonia in patients undergoing different surgeries were analyzed.
    RESULTS There were no statistically significant differences in the time windows for postoperative pneumonia among groups in terms of sociodemographic factors and underlying diseases. However, statistically significant differences were observed in the time windows for postoperative pneumonia based on surgery type, incision type, surgical approach and surgery duration (P < 0.05). The average time for the onset of postoperative pneumonia in 263 patients was 2.00 (1.00, 7.00) days. The postoperative time windows varied for surgeries involving different systems. The peak incidence occurred on day 0 (16 cases) and day 1 (17 cases) after neurological surgery, while the peak incidence for digestive system and orthopedic surgeries was on day 1. The time span for the onset of pneumonia after skin surgeries was wider (0-53 days postoperatively) without a clear peak. In addition, 33.33% of cardiovascular system surgery cases developed pneumonia 10 days postoperatively. There were also significant time differences in the diagnostic elements of postoperative pneumonia, with fever and abnormal white blood cell counts appearing earlier (median appearance time length: 4.00 days) than lung imaging changes (median appearance time length: 7.00 days).
    CONCLUSIONS This study demonstrates significant time differences in the onset of postoperative pneumonia and confirms the significant spatiotemporal heterogeneity in the diagnostic elements of postoperative pneumonia. These findings provide a quantitative basis for developing dynamic, surgery-type-specific monitoring protocols and prevention and control measures for postoperative pneumonia.

     

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