Abstract: Hemodialysis patients exhibit compromised immune function and require long-term repeated vascular punctures as therapeutic approach, the risk of infection increases. Hospital-associated infection in hemodialysis department (center) happens from time to time, which has already become a concern for the medical community, patients and social media. This paper outlines the task origin of China′s "Standard for infection prevention and control in hemodialysis department (center)" (WS/T854-2025), the compilation basis and explanations for its key content, feasibility and implementation recommendations, as well as the clarifications on common issues encountered during its promotion and enforcement.