Abstract:
OBJECTIVE To evaluate the relationship between complicated infections in hospitalized patients with comorbid mental disorders and healthcare resource utilization and to provide references for developing integrated physical and mental health management models suitable for such population.
METHODS This retrospective study analyzed data for the entire year of 2025 from Chinese PLA General Hospital. Patients with infectious diseases were identified via the real-time nosocomial infection surveillance system, while those with mental disorders were identified using ICD-10 codes （F00-F99）. A 1∶1 propensity score matching method was employed to control confounding factors.
RESULTS Among 7 146 enrolled patients with health care-associated infections, 423 had comorbid mental disorders. Post-matching analysis of 416 patient pairs revealed that the mean hospitalization duration for patients with mental disorders （25.62 days） was 2.04 days longer than that for those without （23.58 days）, with anxiety disorders showing the most pronounced prolongation in duration （3.38 days）. However, the mean hospitalization cost for patients with mental disorders （¥63 642.99） was lower than for those without （¥89 794.39）.
CONCLUSION Comorbid mental disorders are associated with prolonged hospitalization in patients with infectious diseases but do not increase healthcare costs correspondingly, suggesting less intensive resource use in clinical management. Future studies should explore integrated and collaborative models combining mental healthcare and infectious disease management.
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