Abstract:
OBJECTIVE To explore the prevalence of
Helicobacter pylori infection and analyze its association with adverse pregnancy outcomes.
METHODS A total of 106 pregnant women complicated with hyperemesis who received routine prenatal examination and gave birth in Keqiao Maternal and Child Health Hospital from Mar 2020 to Mar 2021 were recruited as the study subjects. The prevalence of Hp infection, baseline data, gestational complications and adverse pregnancy outcomes were statistically analyzed, and the association between the Hp infection and the adverse pregnancy outcomes was observed.
RESULTS Among the 106 pregnant women, the incidence rate of Hp infection was 44.34%(47/106), the incidence of adverse pregnancy outcomes was 14.15%(15/106). There was no significant difference in the baseline data between the Hp infection group and the no Hp infection group. The incidence rates of gestational diabetes mellitus and gestational anemia of the Hp infection group were 23.40%(11/47) and 21.28%(10/47), significantly higher than those of the no Hp infection group(
P<0.05). The total incidence of adverse pregnancy outcomes of the Hp infection group was 23.40%(11/47), significantly higher than that of the no Hp infection group(
P<0.05). The Hp infection, gestational diabetes mellitus, gestational anemia and placental abnormalities were the influencing factors for the adverse pregnancy outcomes in the pregnant women(
P<0.05). Logistic regression analysis showed that the Hp infection was the risk factor for the adverse pregnancy outcomes in the pregnant women(
P<0.05).
CONCLUSION The incidence of Hp infection is high among the pregnant women, the Hp infection can increase the risk of adverse pregnant outcomes. It is necessary for the hospital to test in early stage and conduct early treatment so as to improve maternal and infant outcomes.