C-反应蛋白在骨伤患者感染检测中的临床意义
Clinical significance of C-reactive protein in diagnosisof patients with orthopedic infection
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摘要: 目的 综合分析C-反应蛋白(CRP)在骨伤患者感染中的临床检测意义,为治疗骨伤感染患者提供科学依据。方法 选取2013年12月-2014年10月25例确诊为术后感染的骨科病患者为观察组,再选取未发生感染的25例骨科病患者为对照组;采取Array(特种蛋白检测仪)动态检测50例患者CRP在应用抗菌药物前后的动态变化,对比分析观察组与对照组两组患者的CRP值。结果 观察组患者CRP为(6.8±3.3)mg/L,对照组为(3.6±1.2)mg/L,两组数据比较,差异有统计学意义(P<0.05);观察组25例患者中男13例,CRP治疗前阳性10例,治疗后阳性4例;观察组25例患者中女12例,CRP治疗前阳性8例,治疗后阳性3例;两组数据比较差异无统计学意义。结论 CRP的动态检测能够对诊断骨伤感染患者提供重要的临床诊断价值。Abstract: OBJECTIVE To comprehensively analyze the clinical significance of C-reactive protein (CRP) in detecting orthopedic infection, so as to provide a scientific basis for the treatment of orthopedic infection. METHODS The 25 orthopedic cases diagnosed with postoperative infection during Dec. 2013 to Oct. 2014 were selected as the observation group and 25 uninfected patients were selected as the control group. The array (special protein detector) was used for dynamic detection of CRP in the 50 patients before and after the use of antibiotics to compare CRP values between the two groups. RESULTS CRP was (6.8±3.3) mg/L in the observation group and(3.6±1.2)mg/L in the control group, with significant differences (P<0.05). CONCLUSION The dynamic detection of CRP can provide important clinical diagnostic value in the diagnosis of infection in orthopedic patients.
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