OBJECTIVE To explore the clinical value of screening of hepatitis B surface antigen (HBsAg), antibodies to treponema pallidum (anti-TP) and human immunodeficiency virus (HIV) antibody among people receiving premarital health check-up in control of infectious disease.

METHODS A retrospective analysis was performed in Bishan District of Chongqing from Jan 2020 to Dec 2022. Among them, 24 684 cases were screened for HBsAg, 25 140 cases were screened for treponema pallidum antibody, and 23 553 cases were screened for HIV antibody. At the same time, the data of people receiving premarital medical examination between 2018 and 2019 were retrospectively analyzed. Blood samples (5 ml) collected from all the participants in the fasting state were used to separate the serum by centrifugation. HBsAg, anti-TP and HIV antibody were detected by enzyme-linked immunosorbent assay. The negative and positive infection rates among people receiving premarital medical examination were investigated, and the data of different years, both sex and different ages were collected and statistically analyzed.

RESULTS From 2020 to 2022, the positive rates of HBsAg, anti-TP and HIV were 6.34%, 2.46% and 0.34%, respectively. There were some differences in the distribution ratio of infectious diseases indicators between both sex: the prevalence rates of HBsAg and HIV in men were higher (P < 0.05), while the prevalence rate of syphilis in women was higher. There were significant differences in the distribution ratios of the three infection indicators among patients of different ages (P < 0.05).

CONCLUSION The screening of infectious indicators in people receiving premarital medical examination can reflect the epidemiological distribution of infectious diseases in the population. It is convenient for medical staff to take preventive measures for this population, which can effectively avoid the occurrence of subsequent hospital infections of such diseases.