OBJECTIVE  To analyze the symptoms and influencing factors of patients with SARS-CoV-2 in a hospital.

METHODS  From Dec. 22, 2022 to Jan. 10, 2023, the basic demographic information, main clinical symptoms, epidemiological history, vaccination history, smoking and drinking history, and drug use during infection of patients with confirmed SARS-CoV-2 infection in the 305 Hospital of PLA were collected, and the data were statistically described and analyzed.

RESULTS  A total of 431 cases were collected, including 331 males (76.80%), aged 21-30 years, and 6% of the infected people had underlying diseases. 379 people (87.94%) had infection related symptoms, mainly including fever, cough and expectoration, dry throat and sore throat, nasal congestion and runny nose, body pain, etc. The duration of symptoms was concentrated in 2.00-4.00 days, and the drugs were mainly Lianhua Qingwen, ibuprofen, etc. The positive rate and severity of symptoms of female and non-smokers were higher than those of male and smokers. The binary logistic regression model showed that male and smoking might be the protective factors of the model.

CONCLUSIONS  The symptoms of the SARS-CoV-2 in 431 patients were mainly fever, cough and expectoration, dry and sore throat, nasal congestion and runny nose, physical pain, etc., which were predominately mild diseases. The population were in good health and young, which might produce a protective effect greater than that brought about by gender and smoking.