Clinical characteristics of hyperlipidemic acute pancreatitis and non-hyperlipidemic acute pancreatitis and C-reactive protein in assessment of its severity

OBJECTIVE To investigate the clinical characteristics of hyperlipidemic acute pancreatitis and non-hyperlipidemic acute pancreatitis and the value of C-reactive protein in assessing its severity. METHODS A total of 80 patients with hyperlipidemic acute pancreatitis were selected as hyperlipidemia group and 80 patients with non-hyperlipidemic acute pancreatitis were selected as nonhyperlipidemia group from Jan. 2012 to Dec. 2016. The clinical data of age, gender, duration of abdominal pain, interval time of abdominal pain to admission, days of hospitalization and complications were statistically analyzed, and serum C-reactive protein levels were determined by automatic biochemical analyzer. The clinical characteristics and CRP levels of the two groups of patients were observed and analyzed. RESULTS The length of hospital stay in hyperlipidemia group was shorter than that in non-hyperlipidemia group (P<0.05). The recurrence rates of male, fatty liver, diabetes mellitus and acute pancreatitis in hyperlipidemia group were higher than those in non-hyperlipidemia group (P<0.05). The levels of serum CRP at 1, 3, 5 and 7 d of hyperlipidemia group were (51.21±18.57)mg/L, (195.46±64.35)mg/L, (121.35±46.57)mg/L and (64.25±18.54)mg/L, respectively, which were higher than those of non-hyperlipidemia group (P<0.05). The levels of serum CRP at 1, 3, 5 and 7 d of hyperlipidemia group of mild, moderate and severe acute pancreatitis had significant differences compared with those of non-hyperlipidemia group (P<0.05). CONCLUSION The age of patients with hyperlipidemia acute pancreatitis is low, with many complications and high recurrence rate. The C-reactive protein levels in patients with hyperlipidemia acute pancreatitis and non-hyperlipidemic acute pancreatitis with different severities are different.