Analysis of surveillance results of hospital associated invasive candidiasis in Grade-A tertiary hospital from 2015 to 2019

OBJECTIVE To investigate the characteristics of the epidemiology of hospital associated invasive candidiasis（HAIC） in a Grade-A tertiary hospital from 2015 to 2019, and to explore the risk factors for HAIC, so as to provide evidence for the prevention and control of HAIC. METHODS HAIC was diagnosed according to the unified diagnostic criteria. The clinical information of HAIC confirmed cases in this hospital from 2015 to 2019 were collected, including the patient′s age, gender, department and other clinical epidemiological data and infection characteristics such as infection strain and infection site. The epidemiological characteristics of HAIC in the hospital from 2015 to 2019 were analyzed. RESULTS From 2015 to 2019, there were a total of 281 205 adult patients（hospitalization duration ＞48h） in the hospital. HAIC occurred in 130 patients, with an incidence rate of 0.46‰. The incidence of HAIC in male patients was higher than that in female patients（P＜0.05）; the incidence of HAIC in elderly patients was higher than that in young patients（P＜0.05）; the high incidence department of HAIC was ICU（P＜0.05）. The pathogenic strains were mainly Candida albicans（69/130, 53.08%）. The first two main infection sites were bloodstream infections（54/130, 41.54%）. and abdominal（pelvic） infection（50/130, 38.46%）. CONCLUSION The main pathogenic strain of HAIC is Candida albicans, and the main infection site is bloodstream infection. Male patients and elderly patients are high-risk groups for HAIC, and ICU is a high-risk department for HAIC.